Syncop
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Demo data. This console is backed by an in-memory sample dataset. Signing here is a UI demonstration only — it is not a validated 21 CFR Part 11 electronic signature, and the audit chain it appends to is rebuilt from seed data on every restart.

Cohorts

STU-2026-089 — Phase III Oncology — Compound SYN-441

Ledger (PDF/A) Allocation CSV Safety CSV Ledger CSV

CohortGrid holds each cohort's slots. Site staff reserve a slot for a screened candidate while screening completes; a reservation lapses unless it is confirmed. Every reservation and release is written to the audit ledger. This page updates as soon as anyone, at any site, changes a slot.

Dose level 1 DL1

Open 25 mg QD oral

3 slots: 3 available — plus 1 held back for replacements

168 h between first doses · 28-day DLT window

Safety gate open No subject dosed yet: the first may be dosed.
Escalation (3+3): Wait 3 place(s) at this dose are not yet evaluable: still to be filled, or a subject has not completed their DLT window.
  • Slot 1 Available
  • Slot 2 Available
  • Slot 3 Available
  • Replacement 4 Held back

Site staff with a role at an active site reserve slots. Sign in to reserve.

Dose level 2 DL2

Planned 50 mg QD oral

3 slots: 3 available — plus 1 held back for replacements

168 h between first doses · 28-day DLT window

Safety gate open No subject dosed yet: the first may be dosed.
  • Slot 1 Available
  • Slot 2 Available
  • Slot 3 Available
  • Replacement 4 Held back

Dose level 3 DL3

Planned 100 mg QD oral

3 slots: 3 available — plus 1 held back for replacements

168 h between first doses · 28-day DLT window

Safety gate open No subject dosed yet: the first may be dosed.
  • Slot 1 Available
  • Slot 2 Available
  • Slot 3 Available
  • Replacement 4 Held back